APOE Antikörper (C-Term)

Produktnummer ABIN374539

Dieser Ziege Polyklonal Antikörper detektiert spezifisch APOE in WB, IHC (p) und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für APOE Antikörper (C-Term) (ABIN374539)

Target: APOE (Apolipoprotein E (APOE))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser APOE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-APOE Antikörper

Bindungsspezifität: C-Term

Sequenz: C-VGTSAAPVPS DNH

Spezifität: This antibody recognizes Apolipoprotein E (C-term).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the C Terminus of the protein sequence according to NP_000032.1. Genename: APOE

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western blot: 0.1 - 0.3 μg/mL. Immunohistochemistry on paraffin sections: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu APOE

Target: APOE (Apolipoprotein E (APOE))

Andere Bezeichnung: Apolipoprotein E (Apo E)

Hintergrund: Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease by affecting amyloid-beta deposition.Synonyms: Apo-E, ApoE

Gen-ID: 348, 9606

UniProt: P02649

Pathways: Regulation of Cell Size, Lipid Metabolism