Choline Acetyltransferase Antikörper (C-Term)

Produktnummer ABIN374515

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch Choline Acetyltransferase in WB. Er zeigt eine Reaktivität gegenüber Human, Hund, Schwein und Schimpanse.

Kurzübersicht für Choline Acetyltransferase Antikörper (C-Term) (ABIN374515)

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Reaktivität: Human, Hund, Schwein, Schimpanse

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Choline Acetyltransferase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Choline Acetyltransferase Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to CHAT.

Kreuzreaktivität (Details): Species reactivity (expected):Canine, Porcine.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence CKEKATRPSQGHQP, from the C Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/32000. Western Blot: 0.03 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Choline Acetyltransferase

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Andere Bezeichnung: CHAT

Hintergrund: Choline acetyltransferase (ChAT) catalyzes the synthesis of the neurotransmitter acetylcholine (ACh) from choline and acetyl-CoA in cholinergic neurons. ChAT serves as a specific marker for cholinergic neurons in both peripheral and central nervous systems. Dysfunction of cholinergic neurons underlies aspects of clinical symptoms found in neurological and psychiatric disorders such as Alzheimer's disease, Down and Rett syndromes. Choline acetyltransferase recruits choline for the synthesis of acetylcholine at preganglionic parasympathetic and sympathetic fibres. It is also present at parasympathetic postganglionic fibres.Synonyms: CHOACTase, ChAT, Choline O-acetyltransferase, Choline acetylase, EC=2.3.1.6

Gen-ID: 1103

NCBI Accession: NP_001136401

UniProt: P28329

Pathways: Skeletal Muscle Fiber Development