Annexin A2 Antikörper (N-Term)

Produktnummer ABIN374164

Dieser Ziege Polyklonal Antikörper detektiert spezifisch Annexin A2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh) und Schwein.

Kurzübersicht für Annexin A2 Antikörper (N-Term) (ABIN374164)

Target: Annexin A2 (ANXA2)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Annexin A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Annexin A2 Antikörper

Bindungsspezifität: N-Term

Sequenz: STVHEILCKL SLEGD

Spezifität: This antibody is expected to recognize both reported isoforms.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Cow, and Pig.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide from N Terminus of the protein sequence according to NP_001002858.1, NP_004030.1, NP_001002857.1, NP_001129487.1. Genename: ANXA2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 4000. Western blot: 1-3 μg/mL. Approx 35 kDa band observed in lysates of cell lines A431 andA549 (calculated MW of 38.6 kDa according to NP_004030.1 and NP_001002857.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.

Details zu Annexin A2

Target: Annexin A2 (ANXA2)

Andere Bezeichnung: Annexin A2 / ANXA2

Hintergrund: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin II is a calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: ANX2, ANX2L4, Annexin II, Annexin-2, CAL1H, Calpactin I heavy chain, Chromobindin-8, LPC2D, Lipocortin II, Placental anticoagulant protein IV, Protein I, p36

Gen-ID: 302

NCBI Accession: NP_001002858

UniProt: P07355

Pathways: S100 Proteine