Fgr Antikörper (C-Term)

Produktnummer ABIN374126

Produktdetails anti-Fgr Antikörper

Target: Fgr (FGR) (Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Fgr Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: C-TSAEPQYQPG DQT

Spezifität: This antibody detects FGR / SRC2 at C-term.

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_001036194.1, NP_001036212.1, NP_005239.1 Genename: FGR

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 1000. Western Blot: 0.5-2 μg/mL. Approx 60 kDa band seen in Mouse Spleen extracts.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Details zu Fgr

Target: Fgr (FGR) (Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))

Andere Bezeichnung: FGR / SRC2 (FGR Produkte)

Synonyme: SRC2 antikoerper, c-fgr antikoerper, c-src2 antikoerper, p55-Fgr antikoerper, p55c-fgr antikoerper, p58-Fgr antikoerper, p58c-fgr antikoerper, FGR proto-oncogene, Src family tyrosine kinase antikoerper, FGR antikoerper, Fgr antikoerper

Hintergrund: Fgr is a member of the Src family of non-receptor tyrosine kinases. It is expressed in neutrophils, monocytes, macrophages and natural killer cells. Expression of Fgr is developmentally regulated and required in normal myelomonocytic differentiation in vivo. HL-60 cells induced to differentiate with retinoic acid express high levels of Fgr.Synonyms: C-FGR, P55-FGR, Proto-oncogene tyrosine-protein kinase FGR

Gen-ID: 2268

NCBI Accession: NP_001036194

UniProt: P09769

Pathways: Sensory Perception of Sound, Stem Cell Maintenance, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling