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Fgr Antikörper (N-Term)

FGR Reaktivität: Human WB, IHC (p), IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN359981
  • Target Alle Fgr (FGR) Antikörper anzeigen
    Fgr (FGR) (Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-40, N-Term
    Reaktivität
    • 73
    • 18
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 69
    • 4
    • 3
    Kaninchen
    Klonalität
    • 73
    • 2
    Polyklonal
    Konjugat
    • 33
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Fgr Antikörper ist unkonjugiert
    Applikation
    • 42
    • 35
    • 23
    • 13
    • 13
    • 9
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognizes Human FGR (N-term).
    Aufreinigung
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    KLH conjugated synthetic peptide between 11~40 amino acids from the N-terminal region of Human FGR
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product FGR Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    Fgr (FGR) (Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
    Andere Bezeichnung
    FGR / SRC2 (FGR Produkte)
    Synonyme
    SRC2 antikoerper, c-fgr antikoerper, c-src2 antikoerper, p55-Fgr antikoerper, p55c-fgr antikoerper, p58-Fgr antikoerper, p58c-fgr antikoerper, FGR proto-oncogene, Src family tyrosine kinase antikoerper, FGR antikoerper, Fgr antikoerper
    Hintergrund
    FGR is a member of the Src family of protein tyrosine kinases (PTKs). This protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. It localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this protein.Synonyms: C-FGR, P55-FGR, Proto-oncogene tyrosine-protein kinase FGR
    Gen-ID
    2268, 9606
    UniProt
    P09769
    Pathways
    Sensory Perception of Sound, Stem Cell Maintenance, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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