RAPSN Antikörper (C-Term)

Produktnummer ABIN372886

Produktdetails anti-RAPSN Antikörper

Target: RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAPSN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to Receptor-associated Protein Of The Synapse, 43 kDa (RAPSN).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections: 10 - 20 μg/mL. Western blot: 1 μg/mL. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.01 % sodium azide and 50 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu RAPSN

Target: RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))

Andere Bezeichnung: RAPSN / RNF205 (RAPSN Produkte)

Hintergrund: Nicotinic acetylcholine receptors (AChRs) are organized into high-density postsynaptic clusters at the motor endplate that are critical for efficient synaptic transmission. The organization of AChRs is carried out by the 43 kDa cytoplasmic protein rapsyn. Studies have indicated that mutations which impair the activity of rapsyn can lead to the formation of congenital myasthenic syndrome (CMS). CMS is characterized by poor development of the postsynaptic region.Synonyms: 43 kDa postsynaptic protein, 43 kDa receptor-associated protein of the synapse, Acetylcholine receptor-associated 43 kDa protein, RAPsyn, RING finger protein 205

Gen-ID: 5913

NCBI Accession: NP_005046

UniProt: Q13702