ICAM5 Antikörper (C-Term)

Produktnummer ABIN372797

Der Ziege Polyklonal anti-ICAM5 Antikörper wird verwendet zum Nachweis von ICAM5 in Proben von Human, Maus und Ratte. Er wurde validiert für IHC (p) und EIA.

Kurzübersicht für ICAM5 Antikörper (C-Term) (ABIN372797)

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ICAM5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-ICAM5 Antikörper

Bindungsspezifität: C-Term

Sequenz: c-ESPAEGEVFA IQ

Spezifität: Recognizes Intercellular Adhesion Molecule 5 (ICAM5).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Bovine and Porcine.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide from the C-terminus of Human ICAM5 (NP_003250.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/128000. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH 7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu ICAM5

Target: ICAM5 (Intercellular Adhesion Molecule 5 (ICAM5))

Andere Bezeichnung: ICAM5

Hintergrund: ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.Synonyms: ICAM-5, Intercellular Adhesion Molecule 5, TLCN, TLN, Telencephalin

Gen-ID: 7087

NCBI Accession: NP_003250

UniProt: Q9UMF0

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location