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TAO Kinase 2 Antikörper (pSer181)

TAOK2 Reaktivität: Human, Maus, Ratte, Hund, Xenopus laevis, Zebrafisch (Danio rerio), Fink WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN372726
  • Target Alle TAO Kinase 2 (TAOK2) Antikörper anzeigen
    TAO Kinase 2 (TAOK2)
    Bindungsspezifität
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    pSer181
    Reaktivität
    Human, Maus, Ratte, Hund, Xenopus laevis, Zebrafisch (Danio rerio), Fink
    Wirt
    • 33
    • 3
    Kaninchen
    Klonalität
    • 33
    • 3
    Polyklonal
    Konjugat
    • 16
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TAO Kinase 2 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 18
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    Specific for the ~120k TAO2 phosphorylated at Ser181 in Western blots. Immunolabeling is completely eliminated by treatment with lambda-phosphatase.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Canine, Finch, Xenopus and Zebrafish.
    Species reactivity (tested):Human, Mouse and Rat.
    Aufreinigung
    Affinity Chromatography via sequential chromatography on phospho- and dephosphopeptide affinity columns.
    Immunogen
    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser181 of TAO2.
    Isotyp
    IgG
    Top Product
    Discover our top product TAOK2 Primärantikörper
  • Applikationshinweise
    Western blot: 1/1,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody undiluted (in aliquots) at-20 °C.
  • Target
    TAO Kinase 2 (TAOK2)
    Abstract
    TAOK2 Produkte
    Synonyme
    MAP3K17 antikoerper, PSK antikoerper, PSK1 antikoerper, PSK1-BETA antikoerper, TAO1 antikoerper, TAO2 antikoerper, Tao2 antikoerper, 1110033K02Rik antikoerper, B230344N16 antikoerper, mKIAA0881 antikoerper, TAOK2 antikoerper, map3k17 antikoerper, psk antikoerper, psk1 antikoerper, tao1 antikoerper, tao2 antikoerper, TAO kinase 2 antikoerper, TAO kinase 2 L homeolog antikoerper, serine/threonine-protein kinase TAO2 antikoerper, TAOK2 antikoerper, Taok2 antikoerper, taok2.L antikoerper, taok2 antikoerper, LOC100085396 antikoerper
    Hintergrund
    In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEKs) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999, Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPKs (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.Synonyms: KFC-C, KIAA0881, Kinase from chicken homolog C, MAP3K17, PSK-1, PSK1, Prostate-derived STE20-like kinase 1, Serine/threonine-protein kinase TAO2, Thousand and one amino acid protein 2, UNQ2971/PRO7431
    Gen-ID
    9344
    NCBI Accession
    NP_004774
    UniProt
    Q9UL54
    Pathways
    Cell-Cell Junction Organization
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