TAO Kinase 2 Antikörper (pSer181)

Produktnummer ABIN6656508

Produktdetails anti-TAO Kinase 2 Antikörper

Target: TAO Kinase 2 (TAOK2)

Bindungsspezifität: pSer181

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAO Kinase 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: Anti-TAO2 pS181 Antibody is directed against human TAO2 protein phosphorylated at Ser181. TAO2 pS181 antibodies are prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. Immunolabeling is completely eliminated by treatment with lambda-phosphatase. Reactivity is expected from the following species based on 100% sequence homology: zebra fish, xenopus, finch and canine.

Immunogen:

Immunogen: Anti-TAO2 pS181 Antibody was produced in rabbit by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser181 of TAO2 protein.

Immunogen Type: Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-TAO2 pS181 (Rabbit) antibody is suitable for use in Western Blotting. Expect a band of approximately 120 kDa in size corresponding to TAO2 protein phosphorylated at Ser181 in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Western Blot Dilution: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Details zu TAO Kinase 2

Target: TAO Kinase 2 (TAOK2)

Andere Bezeichnung: TAO2 (TAOK2 Produkte)

Synonyme: MAP3K17 antikoerper, PSK antikoerper, PSK1 antikoerper, PSK1-BETA antikoerper, TAO1 antikoerper, TAO2 antikoerper, Tao2 antikoerper, 1110033K02Rik antikoerper, B230344N16 antikoerper, mKIAA0881 antikoerper, TAOK2 antikoerper, map3k17 antikoerper, psk antikoerper, psk1 antikoerper, tao1 antikoerper, tao2 antikoerper, TAO kinase 2 antikoerper, TAO kinase 2 L homeolog antikoerper, serine/threonine-protein kinase TAO2 antikoerper, TAOK2 antikoerper, Taok2 antikoerper, taok2.L antikoerper, taok2 antikoerper, LOC100085396 antikoerper

Hintergrund:

Synonyms: Serine/threonine-protein kinase TAO2, Kinase from chicken homolog C, hKFC-C, Prostate-derived sterile 20-like kinase 1, PSK-1, Thousand and one amino acid protein kinase 2

Background: TAO2pS181 Antibody detects TAO2. In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEKs) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK. This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPKs. Autophosphorylation of TAO2 may play a role in the mechanism of TAO2 activation. The MEK binding domain of TA2O is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain. Anti-TAO2 pS181 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: TAOK2

Gen-ID: 9344

UniProt: Q9UL54

Pathways: Cell-Cell Junction Organization