SYN1 Antikörper (pSer603)
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- Target Alle SYN1 Antikörper anzeigen
- SYN1 (Synapsin I (SYN1))
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Bindungsspezifität
- pSer603
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Xenopus laevis, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SYN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- This antibody recognizes ~78k Synapsin I doublet protein phosphorylated at Ser603. Immunolabeling of the synapsin I band is blocked by lambda-phosphatase treatment.
- Kreuzreaktivität (Details)
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Species reactivity (expected):Human, Bovine, Mouse, Xenopus and Zebrafish.
Species reactivity (tested):Rat. - Aufreinigung
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
- Immunogen
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser603 of Synapsin I.
- Isotyp
- IgG
- Top Product
- Discover our top product SYN1 Primärantikörper
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anti-Synapsin I (SYN1) (AA 362-511) antibody
SYN1 Reaktivität: Human WB, ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 7H10G6 unconjugated
anti-Synapsin I (SYN1) (AA 113-420) antibodySYN1 Reaktivität: Maus WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Synapsin I (SYN1) (AA 362-450) antibodySYN1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4H1 unconjugated
anti-Synapsin I (SYN1) (pSer9) antibodySYN1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Synapsin I (SYN1) (pSer9) antibodySYN1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Synapsin I (SYN1) antibodySYN1 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Synapsin I (SYN1) (pSer62), (pSer67) antibodySYN1 Reaktivität: Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-Synapsin I (SYN1) (pSer549) antibodySYN1 Reaktivität: Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Synapsin I (SYN1) (pSer9) antibodySYN1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Synapsin I (SYN1) antibodySYN1 Reaktivität: Human, Maus, Ratte, Rind (Kuh) WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody undiluted (in aliquots) at-20 °C.
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- Target
- SYN1 (Synapsin I (SYN1))
- Andere Bezeichnung
- Synapsin-1 (SYN1 Produkte)
- Hintergrund
- Synapsin I plays a key role in synaptic plasticity in brain (Feng et al., 2002, Nayak et al., 1996). This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation (Jovanovic et al., 2001, Kao et al., 2002). Serine 603 is the site on synapsin I that is phosphorylated by calcium calmodulin kinase II and by p21-activated kinases (Sakurada et al., 2002, Czernik et al., 1987). Phosphorylation of this site is thought to regulate synaptic vesicle function (Nayak et al., 1996, Bahler and Greengard, 1987, McGuinness et al., 1989).Synonyms: Brain protein 4.1, SYN1, Synapsin I
- Gen-ID
- 6853
- NCBI Accession
- NP_008881
- UniProt
- P17600
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