RPH3A Antikörper (C-Term)

Produktnummer ABIN372709

Produktdetails anti-RPH3A Antikörper

Target: RPH3A (Rabphilin 3A (RPH3A))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Non-Human Primate

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPH3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody recognizes the ~82k Rabphilin-3A protein.

Kreuzreaktivität (Details): Species reactivity (expected):Human, Bovine, Canine and non-Human Primates.
Species reactivity (tested):Rat.

Aufreinigung: Affinity Chromatography.

Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region of Rabphilin-3A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C.

Details zu RPH3A

Target: RPH3A (Rabphilin 3A (RPH3A))

Andere Bezeichnung: Rabphilin-3A / RPH3A (RPH3A Produkte)

Synonyme: 2900002P20Rik antikoerper, AU022689 antikoerper, AW108370 antikoerper, CG11556 antikoerper, Dmel\\CG11556 antikoerper, exophilin-1 antikoerper, fc61h10 antikoerper, rph3a antikoerper, wu:fc61h10 antikoerper, rabphilin 3A antikoerper, Rabphilin antikoerper, rabphilin-3a, putative antikoerper, rabphilin-3A antikoerper, rabphilin 3A S homeolog antikoerper, rabphilin 3A homolog (mouse), a antikoerper, RPH3A antikoerper, Rph3a antikoerper, Rph antikoerper, Smp_145120 antikoerper, Tsp_00335 antikoerper, rph3a.S antikoerper, rph3aa antikoerper

Hintergrund: Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994,Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington's disease (Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995,Foletti and Scheller, 2001).Synonyms: Exophilin 1, Exophilin-1, KIAA0985, Rabphilin 3A

Gen-ID: 171039

NCBI Accession: NP_598202

UniProt: P47709

Pathways: Synaptic Vesicle Exocytosis