RPH3A Antikörper (C-Term)

Produktnummer ABIN6658251

Produktdetails anti-RPH3A Antikörper

Target: RPH3A (Rabphilin 3A (RPH3A))

Bindungsspezifität: C-Term

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPH3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität (Details): Cross reactivity with Rab 3A from other species has not been determined, however, the sequence of the immunogen shows 100 % identity to mouse, human, bovine, canine, and non-human primates, therefore, cross reactivity is expected.

Aufreinigung: Anti-Rabphilin 3A antibody is directed against rat rabphilin 3A proteins. Anti-Rabphilin 3A antibodies are affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen:

Immunogen: Anti-Rabphilin 3A Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.

Immunogen Type: Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-Rabphilin 3A (Rabbit) antibody is suitable for use in ELISA, and in western blotting. Expect a band of approximately 82 kDa in size corresponding to rabphilin 3A protein in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Western Blot Dilution: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  Aliquot contents and freeze at -20° C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.

Details zu RPH3A

Target: RPH3A (Rabphilin 3A (RPH3A))

Andere Bezeichnung: Rabphilin 3A (RPH3A Produkte)

Synonyme: 2900002P20Rik antikoerper, AU022689 antikoerper, AW108370 antikoerper, CG11556 antikoerper, Dmel\\CG11556 antikoerper, exophilin-1 antikoerper, fc61h10 antikoerper, rph3a antikoerper, wu:fc61h10 antikoerper, rabphilin 3A antikoerper, Rabphilin antikoerper, rabphilin-3a, putative antikoerper, rabphilin-3A antikoerper, rabphilin 3A S homeolog antikoerper, rabphilin 3A homolog (mouse), a antikoerper, RPH3A antikoerper, Rph3a antikoerper, Rph antikoerper, Smp_145120 antikoerper, Tsp_00335 antikoerper, rph3a.S antikoerper, rph3aa antikoerper

Hintergrund:

Synonyms: Rabphilin 3A Homolog, Rabphilin-3A, RP3A, Rph3A, Exophilin 1, Exophilin-1

Background: Rabphilin 3A antibody detects Rab 3A which is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes. The expression of rabphilin 3A is reduced in an animal model of Huntington's disease. Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner. Anti-Rabphilin 3A antibody is ideal for investigators involved in Signal Transduction, Cell Signaling, and Neuroscience research.

Gene Name: RPH3A

Gen-ID: 171039

UniProt: P47709

Pathways: Synaptic Vesicle Exocytosis