OLIG2 Antikörper

Produktnummer ABIN372693

Dieses Anti-OLIG2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von OLIG2 in WB, IP, IF und IHC (fro). Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für OLIG2 Antikörper (ABIN372693)

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OLIG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-OLIG2 Antikörper

Spezifität: This antibody recognizes the ~32 kDa Olig2 protein in Western blots.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse and Rat.

Aufreinigung: Protein A Chromatography.

Immunogen: Recombinant Mouse Olig2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 1/3000. Immunohistochemistry: 1/1000. Immunocytochemistry: 1/1000. Immunoprecipitation: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 mM Glycine, 200 mM Tris, pH 8.0 without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C.

Referenzen für anti-OLIG2 Antikörper (ABIN372693)

Norwood, Franklin, Sharma, DMello: "Histone deacetylase 3 is necessary for proper brain development." in: The Journal of biological chemistry, Vol. 289, Issue 50, pp. 34569-82, (2014) (PubMed).

Bains, Tourkina, Atkinson, Joseph, Tholanikunnel, Chu, Riemer, Martin, Hoffman: "Loss of caveolin-1 from bronchial epithelial cells and monocytes in human subjects with asthma." in: Allergy, Vol. 67, Issue 12, pp. 1601-4, (2012) (PubMed).

Davies, Goebel-Goody, Coultrap, Browning: "Long term synaptic depression that is associated with GluR1 dephosphorylation but not alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor internalization." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33138-46, (2008) (PubMed).

Guan, Tkatch, Surmeier, Armstrong, Foehring: "Kv2 subunits underlie slowly inactivating potassium current in rat neocortical pyramidal neurons." in: The Journal of physiology, Vol. 581, Issue Pt 3, pp. 941-60, (2007) (PubMed).

Details zu OLIG2

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Andere Bezeichnung: OLIG2

Hintergrund: Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Expressed in the ventral spinal cord as early as 9.5 dpc and scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. From 10.5 through 14.5 dpc, Olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors (Ligon et al., 2007).Synonyms: BHLHB1, Class B basic helix-loop-helix protein 1, OLIG2, Oligo2, Oligodendrocyte transcription factor 2, PRKCBP2, Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, RACK17, bHLHB1

Gen-ID: 10215

NCBI Accession: NP_005797

UniProt: Q13516