STXBP1 Antikörper (pSer515)
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- Target Alle STXBP1 Antikörper anzeigen
- STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
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Bindungsspezifität
- pSer515
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Huhn, Xenopus laevis
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser STXBP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- This antibody recognizes ~65k Munc-18 protein phosphorylated at Ser515. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide.
- Aufreinigung
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
- Immunogen
- Phosphopeptide corresponding to amino acid residues surrounding the phospho- Ser515 of Munc-18.
- Isotyp
- IgG
- Top Product
- Discover our top product STXBP1 Primärantikörper
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anti-Syntaxin Binding Protein 1 (STXBP1) (AA 74-168) antibody
STXBP1 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 6D1 unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 295-594) antibodySTXBP1 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (C-Term) antibodyVerified STXBP1 Reaktivität: Human WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 18-1) antibodySTXBP1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, IP Wirt: Maus Monoclonal 31-Munc unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 245-594) antibodySTXBP1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (C-Term) antibodySTXBP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) antibodySTXBP1 Reaktivität: Human, Maus, Affe WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 74-169) antibodySTXBP1 Reaktivität: Human, Maus WB, ELISA, IHC, IHC (p) Wirt: Maus Monoclonal 6D1 unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) antibodySTXBP1 Reaktivität: Human, Maus, Ratte, Rind (Kuh) WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 184-216), (N-Term) antibodySTXBP1 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Western blot: 1/1000. Immunohistochemistry: 1/400. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% Glycerol.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody undiluted (in aliquots) at-20°C.
- Haltbarkeit
- 12 months
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- Target
- STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
- Andere Bezeichnung
- STXBP1 / UNC18A (STXBP1 Produkte)
- Hintergrund
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Munc-18 (mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin (Ciufo et al., 2005). Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex (Liu et al., 2004). The function of Munc-18 is thought to be regulated by PKC phosphorylation of Ser515 on the Munc-18 protein (Sassa et al., 1996).
Alternate names: N-Sec1, Syntaxin-binding protein 1, Unc-18 homolog, Unc-18-1, Unc-18A - Gen-ID
- 25558
- NCBI Accession
- NP_037170
- UniProt
- P61765
- Pathways
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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