Ephrin B1 Antikörper (pTyr317)
-
- Target Alle Ephrin B1 (EFNB1) Antikörper anzeigen
- Ephrin B1 (EFNB1)
-
Bindungsspezifität
- pTyr317
-
Reaktivität
- Human, Maus, Ratte, Zebrafisch (Danio rerio), Huhn, Rind (Kuh), Xenopus laevis
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser Ephrin B1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Spezifität
- Specific for the ~46k Ephrin-B protein phosphorylated at Tyr317. Immunolabeling of the Ephrin-B band is blocked by lambda-phosphatase treatment
- Kreuzreaktivität (Details)
-
Species reactivity (expected):Human, Bovine, Chicken, Mouse, Xenopus and Zebrafish.
Species reactivity (tested):Rat. - Aufreinigung
- Sequential Chromatography on phospho- and dephosphopeptide affinity columns.
- Immunogen
- Phosphopeptide corresponding to amino acid residues surrounding the phospho Tyr317 of Chicken Ephrin-B.
- Isotyp
- IgG
- Top Product
- Discover our top product EFNB1 Primärantikörper
-
-
- Applikationshinweise
-
Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody undiluted (in aliquots) at-20 °C.
-
- Target
- Ephrin B1 (EFNB1)
- Andere Bezeichnung
- Ephrin-B1 (EFNB1 Produkte)
- Synonyme
- EFNB1 antikoerper, LERK2 antikoerper, Cek5-L antikoerper, EFL-3 antikoerper, Elk-L antikoerper, Epl2 antikoerper, Eplg2 antikoerper, LERK-2 antikoerper, Lerk2 antikoerper, Stra1 antikoerper, CFND antikoerper, CFNS antikoerper, EFL3 antikoerper, EPLG2 antikoerper, cfnd antikoerper, cfns antikoerper, efl3 antikoerper, efnb1-A antikoerper, ephrinB1 antikoerper, eplg2 antikoerper, lerk2 antikoerper, ephrin B1 antikoerper, ephrin-B1 antikoerper, ephrin-B1 L homeolog antikoerper, EFNB1 antikoerper, Efnb1 antikoerper, efnb1 antikoerper, efnb1.L antikoerper
- Hintergrund
- Ephrin-B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development (Flanagan and Vancerhaeghen, 1998, Dufour et al., 2003, Oike et al., 2002). Ephrin-B molecules expressed at the membrane surface bind to the EphB family receptors on target cells during cell-to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin-B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin-B is thought to be a critical component of this reverse signaling event (Palmer et al., 2002). Recent work suggests that phosphorylation of a specific Ephrin-B residue (Tyr298) plays a key role in Ephrin-B signaling (Kalo, et al., 2001).Synonyms: CEK5 LIgand, CEK5-L, EFL-3, EFL3, EFNB1, ELK-L, EPH-related receptor tyrosine kinase ligand 2, EPLG2, LERK-2, LERK2
- Gen-ID
- 395896
- NCBI Accession
- NP_990366
- UniProt
- O73612
- Pathways
- RTK Signalweg
-