AMPD1 Antikörper (AA 140-190)

Produktnummer ABIN372277

Produktdetails anti-AMPD1 Antikörper

Target: AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))

Bindungsspezifität: AA 140-190

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Affe, Schimpanse, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMPD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody recognizes AMPD1.

Kreuzreaktivität (Details): Species reactivity (expected):Bovine, Chimpanzee, Dog (Canine), Monkey, Mouse, Rat and Zebrafish.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to a portion of the amino acids 140-190 of Human AMPD1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 0.5-2.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu AMPD1

Target: AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))

Andere Bezeichnung: AMP Deaminase 1 / AMPD1 (AMPD1 Produkte)

Synonyme: ampd1 antikoerper, MAD antikoerper, MADA antikoerper, AI553520 antikoerper, Ampd-1 antikoerper, Ampd01 antikoerper, RATAMPD01 antikoerper, zgc:77905 antikoerper, adenosine monophosphate deaminase 1 antikoerper, N-acetyl-anhydromuranmyl-L-alanine amidase antikoerper, N-acetylmuramoyl-L-alanine amidase antikoerper, Negative regulator of beta-lactamase expression antikoerper, adenosine monophosphate deaminase 1 (isoform M) antikoerper, AMPD1 antikoerper, ampD1 antikoerper, ampd1 antikoerper, Ampd1 antikoerper

Hintergrund: AMP deaminase (AMPD) is an allosteric enzyme that plays a critical role in energy metabolism. There are three functional isoforms of AMPD. AMPD1 is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. Defects in AMPD1 are the cause of adenosine monophosphate deaminase deficiency muscle type (AMPDDM). AMPDDM is a metabolic disorder resulting in exercise-related myopathy. It is characterized by exercise-induced muscle aches, cramps, and early fatigue.Synonyms: AMP deaminase isoform M, Myoadenylate deaminase

Molekulargewicht: 87 kDa.

Gen-ID: 270

NCBI Accession: NP_000027

UniProt: P23109