AMPD1 Antikörper (AA 140-190)

Produktnummer ABIN372277

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch AMPD1 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Affe, Zebrafisch (Danio rerio) und Schimpanse.

Kurzübersicht für AMPD1 Antikörper (AA 140-190) (ABIN372277)

Target: AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Affe, Zebrafisch (Danio rerio), Schimpanse

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMPD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-AMPD1 Antikörper

Bindungsspezifität: AA 140-190

Spezifität: This antibody recognizes AMPD1.

Kreuzreaktivität (Details): Species reactivity (expected):Bovine, Chimpanzee, Dog (Canine), Monkey, Mouse, Rat and Zebrafish.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to a portion of the amino acids 140-190 of Human AMPD1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western Blot: 0.5-2.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % Sodium Azide as preservative and 0.2 % Gelatin as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu AMPD1

Target: AMPD1 (Adenosine Monophosphate Deaminase 1 (AMPD1))

Andere Bezeichnung: AMP Deaminase 1 / AMPD1

Hintergrund: AMP deaminase (AMPD) is an allosteric enzyme that plays a critical role in energy metabolism. There are three functional isoforms of AMPD. AMPD1 is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. Defects in AMPD1 are the cause of adenosine monophosphate deaminase deficiency muscle type (AMPDDM). AMPDDM is a metabolic disorder resulting in exercise-related myopathy. It is characterized by exercise-induced muscle aches, cramps, and early fatigue.Synonyms: AMP deaminase isoform M, Myoadenylate deaminase

Molekulargewicht: 87 kDa.

Gen-ID: 270

NCBI Accession: NP_000027

UniProt: P23109