TUBB3 Antikörper

Produktnummer ABIN371847

Der Maus Monoklonal anti-TUBB3 Antikörper (Klon AA10) (ABIN371847) detektiert spezifisch TUBB3 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Ratte.

Kurzübersicht für TUBB3 Antikörper (ABIN371847)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TUBB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: AA10

Produktdetails anti-TUBB3 Antikörper

Spezifität: AM08272PU-N is specific for the ~55 kDa beta III Tubulin protein. Note: This clone is similar to the Monoclonal antibody Tuj1.

Kreuzreaktivität (Details): Species reactivity (tested):Rat.

Produktmerkmale: Synonyms: Tubulin beta-3 chain, Tubulin beta-III, Tubulin beta-4

Aufreinigung: Protein G Chromatography.

Immunogen: Synthetic peptide corresponding to beta III tubulin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/10,000. Immunohistochemistry: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Andere Bezeichnung: TUBB3 / TUBB4

Hintergrund: Tubulin is the major constituent of microtubules, existing as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al., 1990). Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al., 2003)Synonyms: Tubulin beta-3 chain, Tubulin beta-4, Tubulin beta-III

Gen-ID: 246118

UniProt: Q4QRB4

Pathways: Microtubule Dynamics, M Phase