TOLLIP Antikörper
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- Target Alle TOLLIP Antikörper anzeigen
- TOLLIP (Toll Interacting Protein (TOLLIP))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TOLLIP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA), Flow Cytometry (FACS)
- Spezifität
- This antibody is specific to Human Tollip. Does not react to TLR2, TLR4, TLR6, TLR7, TLR8 and TLR10 recombinant proteins.
- Produktmerkmale
- Synonyms: Toll-interacting protein
- Aufreinigung
- Purified
- Immunogen
- Recombinant Tollip.
- Klon
- SB40a
- Isotyp
- IgG2a
- Top Product
- Discover our top product TOLLIP Primärantikörper
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anti-Toll Interacting Protein (TOLLIP) (AA 1-274) antibody
TOLLIP Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 1-274) antibodyTOLLIP Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 1A5-2A3 unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 19-254) antibodyTOLLIP Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 221-250), (C-Term) antibodyTOLLIP Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB4409 unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 1-274) antibodyTOLLIP Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 1-274) antibodyTOLLIP Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 28-261) antibodyTOLLIP Reaktivität: Human WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 86-163) antibodyTOLLIP Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (N-Term) antibodyTOLLIP Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Affe, Meerschweinchen, Pferd, Kaninchen, Hund, Hamster WB Wirt: Kaninchen Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 61-274) antibodyTOLLIP Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal k1B17 unconjugated
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- Applikationshinweise
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ELISA. Western Blot. Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- 100 mM Borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Haltbarkeit
- 12 months
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- Target
- TOLLIP (Toll Interacting Protein (TOLLIP))
- Andere Bezeichnung
- TOLLIP (TOLLIP Produkte)
- Hintergrund
- Toll like protein is a component of the signaling pathway of IL1 and Toll like receptors. It inhibits cell activation by microbial products. Tollip recruits IRAK1 to the IL1 receptor complex and inhibits IRAK1 phosphorylation and kinase activity. It oligomerizes and binds to TLR2 and the TLR4-MD2 complex via its C terminus. It exists as a complex with IRAK1 in unstimulated cells. Upon IL1 signaling, Tollip binds to the activated IL1 receptor complex containing IL-1RI, IL-1RacP and the adapter protein MyD88, where it interacts with the TIR domain of IL-1RacP. MyD88 then triggers IRAK1 autophosphorylation, which in turn leads to the dissociation of IRAK1 from Tollip and IL-1RAcP.Synonyms: Toll-interacting protein
- Gen-ID
- 54472
- UniProt
- Q9H0E2
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