GM-CSF Antikörper

Produktnummer ABIN371618

Der Ratte Monoklonal Anti-GM-CSF-Antikörper wurde für FACS, IF, EIA und ELISA (Detection) validiert. Er ist geeignet, GM-CSF in Proben von Human zu detektieren.

Kurzübersicht für GM-CSF Antikörper (ABIN371618)

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser GM-CSF Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA), ELISA (Detection)

Klon: BVD2-21C11

Produktdetails anti-GM-CSF Antikörper

Spezifität: This antibody is specific to Human Granulocyte/Macrophage-Colony Stimulating Factor (GM-CSF)1-4. The BVD2-21C11 antibody has been reported to cross react with GM-CSF from Rhesus monkey. (This is a Neutralizing antibody.)

Produktmerkmale: Synonyms: CSF2, GMCSF, Sargramostim, Molgramostin, Granulocyte-macrophage colony-stimulatingfactor, Colony stimulating factor 2

Aufreinigung: Purified

Immunogen: E. coli-expressed human GM-CSF.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA Detection: Biotinylated Monoclonal antibody ABIN371617 is the preferreddetection antibody in a Sandwich ELISA for quantifying human GM-CSF protein levels. (Ref.1-4)Immunofluorescence/Flow Cytometry: This antibody is useful for Intracytoplasmic stainingand Flow Cytometric analysis to identify and enumerate GM-CSF-positive cells within mixedcell populations. Recombinant human GM-CSF (Cat#ABIN371618 should be used as a Specificity Control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 100 mM Borate buffered saline, pH 8.0 without preservatives or amine-containing buffer salts.

Konservierungsmittel: Without preservative

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu GM-CSF

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Andere Bezeichnung: GM-CSF

Hintergrund: GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity.Synonyms: CSF2, Colony stimulating factor 2, GMCSF, Granulocyte-macrophage colony-stimulating factor, Molgramostin, Sargramostim

Gen-ID: 1437

UniProt: P04141

Pathways: JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin