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CD51 Antikörper

ITGAV Reaktivität: Human FACS, IHC (fro) Wirt: Maus Monoclonal 13C2 unconjugated
Produktnummer ABIN371554
  • Target Alle CD51 (ITGAV) Antikörper anzeigen
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Reaktivität
    • 103
    • 57
    • 23
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 65
    • 38
    • 13
    Maus
    Klonalität
    • 58
    • 57
    Monoklonal
    Konjugat
    • 61
    • 10
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD51 Antikörper ist unkonjugiert
    Applikation
    • 55
    • 50
    • 30
    • 30
    • 24
    • 15
    • 14
    • 14
    • 13
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Produktmerkmale
    Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha
    Aufreinigung
    Purified
    Klon
    13C2
    Isotyp
    IgG1
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  • Applikationshinweise
    Flow Cytometry: < / = 1 μg/10^6 cells. Immunohistochemistry on Frozen Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Andere Bezeichnung
    CD51 / ITGAV (ITGAV Produkte)
    Hintergrund
    Integrin alpha V chain interacts with the integrin beta 3 subunit/CD61 to form the alpha-V-beta-3 heterodimer/vitronectin receptor. It is expressed on endothelial cells, some activated leukocytes, NK cells, macrophages, neutrophils, and platelets. Integrin alpha V also forms heterodimers with the integrin beta 1, beta 5, beta 6, and beta 8 subunits. Alpha-V-beta-3 is an activation dependent receptor for platelet attachment and spreading on vitronectin and other matrix components. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Alpha-V/beta-6 binds to foot-and-mouth disease virus (FMDV) VP1 protein and acts as a receptor for this virus By similarity. Alpha-V/beta-6 binds to coxsackievirus A9 and coxsackievirus B1 capsid proteins and acts as a receptor for these viruses. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31. (Ref.1-4)Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha
    UniProt
    P06756
    Pathways
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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