CD8B Antikörper

Produktnummer ABIN371369

Der Maus Monoklonal Anti-CD8B Antikörper wurde für FACS, IP und IHC (fro) validiert. Er ist geeignet, CD8B in Proben von Huhn zu detektieren.

Kurzübersicht für CD8B Antikörper (ABIN371369)

Target: CD8B (CD8b Molecule (CD8B))

Reaktivität: Huhn

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD8B Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: EP42

Produktdetails anti-CD8B Antikörper

Spezifität: This antibody recognizes beta chain of Chicken CD8 (Mr. 34 kDa).

Produktmerkmale: Synonyms: eu2, Ly3, LYT3, CD8B1, T cell surface glycoprotein CD8 beta chain

Aufreinigung: Purified

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD8B

Target: CD8B (CD8b Molecule (CD8B))

Andere Bezeichnung: CD8 beta

Hintergrund: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Chicken CD8 is expressed on approximately 80 % of thymocytes, 45 % of blood mononuclear cells and 50 % of spleen cells, but <1 % of cells in the bursa and bone marrow. (Ref.1,2)Synonyms: CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain

Gen-ID: 396175

UniProt: Q90769

Pathways: T-Zell Rezeptor Signalweg