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CD5 Antikörper

CD5 Reaktivität: Cat FACS, IP, IHC (fro) Wirt: Maus Monoclonal f43 unconjugated
Produktnummer ABIN371316
  • Target Alle CD5 Antikörper anzeigen
    CD5
    Reaktivität
    • 226
    • 84
    • 57
    • 27
    • 22
    • 19
    • 15
    • 12
    • 12
    • 11
    • 11
    • 11
    • 9
    • 2
    • 1
    Cat
    Wirt
    • 175
    • 79
    • 56
    • 1
    Maus
    Klonalität
    • 237
    • 71
    • 1
    Monoklonal
    Konjugat
    • 111
    • 36
    • 32
    • 26
    • 15
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD5 Antikörper ist unkonjugiert
    Applikation
    • 237
    • 103
    • 70
    • 68
    • 61
    • 47
    • 31
    • 28
    • 20
    • 18
    • 13
    • 13
    • 12
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Produktmerkmale
    Synonyms: LEU1, LEU-1, Ly-1, Lyt-1, Lymphocyte antigen T1/Leu-1, T-cell surface glycoprotein CD5
    Aufreinigung
    Purified
    Klon
    F43
    Isotyp
    IgG1
    Top Product
    Discover our top product CD5 Primärantikörper
  • Applikationshinweise
    Flow Cytometry. (Ref.1-2)Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections only). Immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    CD5
    Andere Bezeichnung
    CD5 (CD5 Produkte)
    Hintergrund
    In humans, CD5 is a 55 kDa T lymphocyte single chain transmembrane glycoprotein. It is present on all mature T lymphocytes, on most thymocytes and on many T cell leukemias and lymphomas. It reacts with a subpopulation of activated B cells. CD5/Lyt1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B cell antigen CD72. The frequency of CD5+ B cells exhibits strain dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B1 cells. Binding of CD5 on the T cell surface can augment alloantigen or mitogen induced lymphocyte proliferation and induces increased cytosolic free calcium, IL2 secretion, and IL2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T cell and B cell receptors.Synonyms: LEU-1, LEU1, Ly-1, Lymphocyte antigen T1/Leu-1, Lyt-1, T-cell surface glycoprotein CD5
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