CD21 Antikörper (FITC)

Produktnummer ABIN371307

Produktdetails anti-CD21 Antikörper (FITC)

Target: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Reaktivität: Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD21 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Spezifität: This antibody is specific to Porcine CD21 (Mr. 160 kDa). It stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues: 92-96 % in peripheral blood, 74-98 % in mesenteric lymph nodes, 97-100 % in ileal Peyer's patches (ILPP), 93-97 % in spleen, and 0 % in thymus. The antibody does not stain B cells in cord blood or spleen from pig fetuses (105 days gestation). Does not stain B cells in cord blood or spleen from pig fetuses (105 days gestation).

Produktmerkmale: Synonyms: EBV Receptor, CR2, C3DR, Complement Receptor type 2, Complement C3d Receptor,Epstein-Barr virus Receptor

Klon: BB6-11C9-6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.2-3)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD21

Target: CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

Andere Bezeichnung: CD21 (CR2 Produkte)

Hintergrund: CD21 also known as complement receptor 2 (CR2), C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation, sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.Synonyms: C3DR, C3d receptor, CR2, Complement C3d receptor, Complement receptor type 2, Dendritic Cell Marker, EBV Receptor, Epstein-Barr virus receptor

Gen-ID: 1380

Pathways: Komplementsystem