IL2 Receptor beta Antikörper
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- Target Alle IL2 Receptor beta (IL2RB) Antikörper anzeigen
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser IL2 Receptor beta Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Spezifität
- This antibody recognises beta chain (Mr. 90-100 kDa) of the IL-2 Receptor. It does not block IL-2 binding. (Ref.1)
- Produktmerkmale
- Synonyms: Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL2 Receptor beta, P70-75
- Endotoxin-Niveau
- Low Endotoxin
- Immunogen
- Rat myeloma YB2/0 transfected with truncated mouse IL-2RB cDNA. (Ref. 1)
- Klon
- 5H4
- Isotyp
- IgG2a
- Top Product
- Discover our top product IL2RB Primärantikörper
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anti-Interleukin 2 Receptor, beta (IL2RB) (AA 27-240) antibody
IL2RB Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 1G11C6 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (Internal Region) antibodyIL2RB Reaktivität: Maus, Human, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibodyIL2RB Reaktivität: Human FACS, IP Wirt: Maus Monoclonal TU27 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibodyIL2RB Reaktivität: Human FACS, IP, Func Wirt: Maus Monoclonal TU27 unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) antibody (APC)IL2RB Reaktivität: Human FACS Wirt: Maus Monoclonal TU27 APC
anti-Interleukin 2 Receptor, beta (IL2RB) (Tyr364) antibodyIL2RB Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (AA 1-551) antibodyIL2RB Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (AA 1-551) antibodyIL2RB Reaktivität: Human WB, FACS Wirt: Maus Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (N-Term) antibodyIL2RB Reaktivität: Maus, Human WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 2 Receptor, beta (IL2RB) (AA 27-240) antibodyIL2RB Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Flow Cytometry. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- PBS without preservatives.
- Konservierungsmittel
- Without preservative
- Lagerung
- -20 °C
- Informationen zur Lagerung
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Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Haltbarkeit
- 12 months
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- Target
- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
- Andere Bezeichnung
- CD122 / IL2RB (IL2RB Produkte)
- Hintergrund
- The IL-2 receptor is a complex of three distinct polypeptide chains: (i) the alpha chain which binds IL-2 with low affinity, (ii) the beta chain that binds IL-2 with high affinity, and (ii) the common gamma chain (gc) that does not bind IL-2. (Ref.2) The high affinity receptor complex is an alpha/beta/gamma heterotrimer with a Kd of 1.3 x 10e-11 M. (Ref.2) In mouse spleen, CD122 is expresed on ~30 % of CD8+ cells and all NK cells, but < 1 % of B cells and CD4+ T lymphocytes. In the thymus, its expression is confined to CD4-CD8+ single positive and CD4-CD8- double negative cells. (Ref.4) Cytoplasmic regions of the IL-2R beta chain are involved in IL-2-mediated cellular signaling and, via the interaction of IL-2 and its receptor complex, may be involved in the generation and differentiation of T lymphocytes. (Ref.1,4)Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75
- Gen-ID
- 16185
- UniProt
- P16297
- Pathways
- JAK-STAT Signalweg, Growth Factor Binding
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