CD80 Antikörper
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- Target Alle CD80 Antikörper anzeigen
- CD80
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD80 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
- Spezifität
- This antibody recognises CD80/B7-1 (Mr. 45-47 kDa). 1G10 blocks binding of CTLA-4 to CD80, but it does not block stimulation of T cells by natural antigenpresenting cells. (Ref.2,7).
- Produktmerkmale
- Synonyms: CD28LG, CD28LG1, LAB7, BB1, Activation B7-1 antigen, B7.1, T-lymphocyte activationantigen CD80, CTLA-4 counter-receptor B7.1
- Aufreinigung
- Purified
- Klon
- 1G10
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD80 Primärantikörper
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anti-CD80 (CD80) (AA 35-288) antibody
CD80 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 1G3D7 unconjugated
anti-CD80 (CD80) antibodyCD80 Reaktivität: Maus, Hund FACS, IP, IHC (fro) Wirt: Armenischer Hamster Monoclonal 16-10A1 unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibodyCD80 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-233 unconjugated
anti-CD80 (CD80) (AA 38-246) antibodyCD80 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 FITC
anti-CD80 (CD80) (AA 251-321) antibodyCD80 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 PerCP
anti-CD80 (CD80) (Extracellular Domain) antibody (APC)CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 APC
anti-CD80 (CD80) (Extracellular Domain) antibody (PE)CD80 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-233 PE
anti-CD80 (CD80) antibodyCD80 Reaktivität: Human ELISA, IHC, ICC Wirt: Maus Monoclonal 2A2 unconjugated
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- Applikationshinweise
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Flow Cytometry. (Ref.2,7)Immunoprecipitation. (Ref.7)Functional Assays: In vivo and In vitro blocking of ligand binding. (Ref.7)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Haltbarkeit
- 12 months
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- Target
- CD80
- Andere Bezeichnung
- CD80 (CD80 Produkte)
- Hintergrund
- CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours postactivation. (Ref.1-4) The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex. (Ref.5,6)Synonyms: Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80
- Gen-ID
- 12519
- UniProt
- Q00609
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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