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CD38 Antikörper

Reaktivität: Maus FACS, IP, IHC (fro), Func Wirt: Ratte Monoclonal NIMR-5 unconjugated

Produktnummer ABIN370932

Datenblatt (PDF)

Target Alle CD38 Antikörper anzeigen

CD38
Reaktivität
169

68

25

12

12

12

1

1
Maus
Wirt
108

89

33

1

1

1
Ratte
Passende Sekundärantikörper
Klonalität
156

75

1
Monoklonal
Konjugat
72

16

15

13

13

6

6

6

5

4

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Dieser CD38 Antikörper ist unkonjugiert
Applikation
168

70

47

38

35

26

26

23

18

16

10

7

6

3

2

2

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Spezifität

This antibody is specific to CD38 (Mr. 42-46 kDa). Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis. (Ref.1-8)

Produktmerkmale

Synonyms: cADPr hydrolase 1, T10, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1

Endotoxin-Niveau

Low Endotoxin

Klon

NIMR-5

Isotyp

IgG2a

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anti-CD38 (AA 1-300) antibody
Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD38 (AA 43-300) antibody
Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 5C5C3 unconjugated

anti-CD38 (AA 46-300) antibody
Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD38 (AA 241-270) antibody
Reaktivität: Human FACS, WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD38 antibody
Reaktivität: Human FACS, WB, IHC (fro), IHC (p) Wirt: Maus Monoclonal HIT2 unconjugated

anti-CD38 antibody (APC)
Reaktivität: Human FACS Wirt: Maus Monoclonal HIT2 APC

anti-CD38 antibody (PE)
Reaktivität: Human FACS Wirt: Maus Monoclonal HIT2 PE

anti-CD38 (Internal Region) antibody
Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD38 (AA 171-292) antibody
Reaktivität: Human WB, IF Wirt: Maus Monoclonal 22-CD38 unconjugated

Applikationshinweise

Flow Cytometry. (Ref.1-8)Immunoprecipitation. Immunohistochemistry on Frozen Sections. (Ref.7)Functional Assay: Induction of B lymphocyte proliferation. (Ref.3-8)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.5 mg/mL

Buffer

PBS containing no preservatives.

Konservierungsmittel

Without preservative

Lagerung

-20 °C

Informationen zur Lagerung

Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit

12 months
Target

CD38

Abstract

CD38 Produkte

Hintergrund

Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing Nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRalphabeta+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages.Synonyms: ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, cADPr hydrolase 1

Gen-ID

12494

UniProt

P56528