CD38 Antikörper

Produktnummer ABIN370932

Dieser Anti-CD38 Antikörper ist ein Ratte Monoklonal Antikörper zur Detektion von CD38 in FACS, IP, IHC (fro) und Func. Geeignet für Maus.

Kurzübersicht für CD38 Antikörper (ABIN370932)

Target: CD38

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD38 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Klon: NIMR-5

Produktdetails anti-CD38 Antikörper

Spezifität: This antibody is specific to CD38 (Mr. 42-46 kDa). Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis. (Ref.1-8)

Produktmerkmale: Synonyms: cADPr hydrolase 1, T10, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1

Endotoxin-Niveau: Low Endotoxin

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. (Ref.1-8)Immunoprecipitation. Immunohistochemistry on Frozen Sections. (Ref.7)Functional Assay: Induction of B lymphocyte proliferation. (Ref.3-8)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing no preservatives.

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD38

Target: CD38

Hintergrund: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing Nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRalphabeta+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages.Synonyms: ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, T10, cADPr hydrolase 1

Gen-ID: 12494

UniProt: P56528