CD24 Antikörper (Biotin)

Produktnummer ABIN370872

Dieses Anti-CD24-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von CD24 in FACS, IP und IHC (fro). Geeignet für Maus.

Kurzübersicht für CD24 Antikörper (Biotin) (ABIN370872)

Target: CD24 (CD24 Molecule (CD24))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD24 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 91

Produktdetails anti-CD24 Antikörper (Biotin)

Spezifität: This antibody is specific to Heat Stable Antigen HSA (Mr 35-45 kDa).

Produktmerkmale: Synonyms: X62 heat stable antigen, HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4antigen

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: < / = 2 μg/10^6 cells. (Ref.8)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD24

Target: CD24 (CD24 Molecule (CD24))

Andere Bezeichnung: CD24

Hintergrund: CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. (Ref.1-3) The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. (Ref.4-6) Its ligand is P-selectin (CD62P). (Ref.7) CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. (Ref.1-3). The monoclonal antibody 91 can be used to inhibit B-cell differentiation. (Ref.8)Synonyms: HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, X62 heat stable antigen

Gen-ID: 12484

UniProt: P24807

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation