LC3B Antikörper (N-Term)
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- Target Alle LC3B (MAP1LC3B) Antikörper anzeigen
- LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser LC3B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM)
- Spezifität
- Reacts with LC3B from human, mouse, rat and bovine and Zebrafish
- Kreuzreaktivität (Details)
- Other species have not been tested.
- Aufreinigung
- Antigen affinity purified
- Immunogen
- Synthetic peptide made to the N-terminal region of the human LC3, isoform B protein
- Top Product
- Discover our top product MAP1LC3B Primärantikörper
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- Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/IF(1:2000) FC (1:200) IHC (1:400) WB (1:1000) - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS, Sodium azide 0.05 %
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C/-80 °C
- Informationen zur Lagerung
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- Target
- LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
- Andere Bezeichnung
- Light Chain 3 beta (LC3B) (MAP1LC3B Produkte)
- Synonyme
- ATG8F antikoerper, LC3B antikoerper, MAP1A/1BLC3 antikoerper, MAP1LC3B-a antikoerper, Map1lc3 antikoerper, Mpl3 antikoerper, zbs559 antikoerper, 1010001C15Rik antikoerper, Atg8 antikoerper, LC3b antikoerper, zgc:56434 antikoerper, wu:fb60g11 antikoerper, map1lc3b antikoerper, MGC76283 antikoerper, MAP1LC3B antikoerper, microtubule associated protein 1 light chain 3 beta antikoerper, microtubule-associated protein 1 light chain 3 beta antikoerper, microtubule associated protein 1 light chain 3 beta L homeolog antikoerper, MAP1LC3B antikoerper, Map1lc3b antikoerper, map1lc3b antikoerper, map1lc3b.L antikoerper
- Hintergrund
- Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
- Gen-ID
- 81631
- Pathways
- Autophagie
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