PARK7/DJ1 Antikörper (C-Term)

Produktnummer ABIN363457

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PARK7/DJ1 in WB, ICC, IF, IP und Func. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für PARK7/DJ1 Antikörper (C-Term) (ABIN363457)

Target: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARK7/DJ1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func)

Produktdetails anti-PARK7/DJ1 Antikörper

Bindungsspezifität: AA 150-189, C-Term

Spezifität: Reacts with humanand mouse Protein DJ-1

Kreuzreaktivität: Rind (Kuh), Huhn

Kreuzreaktivität (Details): May cross react with rat, bovine, Zebra fish, Golden hamster and chicken proteins (100 % sequence homology).

Aufreinigung: Antiserum

Immunogen: Synthetic peptide corresponding to the C-terminus (within residues 150-189) of human Park7(DJ-1).

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC1:500 IP1:200 WB1:2 000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 6 months

Details zu PARK7/DJ1

Target: PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

Andere Bezeichnung: Protein DJ-1

Hintergrund: Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.

Gen-ID: 11315

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport