ARNT Antikörper
Kurzübersicht für ARNT Antikörper (ABIN363326)
Target
Alle ARNT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Reacts with human HIF 1 beta /ARNT
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Kreuzreaktivität
- Maus, Rind (Kuh), Schaf, Ratte (Rattus)
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Kreuzreaktivität (Details)
- Cross reacts with proteins from bovine, sheep, mouse, rat and ferret. Not tested in other species.
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Aufreinigung
- Antiserum
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Immunogen
- Fusion protein to human HIF-1 beta
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Applikationshinweise
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
ChIP1:10-1:500 ICC/IF (Negative), IHC1:150, IP1:10-1:500, WB1:2000 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- , Sodium azide 0.02 %
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C/-80 °C
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Informationen zur Lagerung
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
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Andere Bezeichnung
- Hypoxia-Inducible Factor 1-beta
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Hintergrund
- Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
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Gen-ID
- 405
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Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effekt
Target
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