ARNT Antikörper (AA 496-789)

Produktnummer ABIN363204

Dieses Anti-ARNT-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ARNT in WB, IHC, IP, IHC (p), ChIP und GS. Geeignet für Human, Maus, Ratte, Rind (Kuh), Schaf, Schwein, Affe und Frettchen.

Kurzübersicht für ARNT Antikörper (AA 496-789) (ABIN363204)

Target: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Schwein, Affe, Frettchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ARNT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Chromatin Immunoprecipitation (ChIP), Gel Shift (GS)

Klon: H1beta234

Produktdetails anti-ARNT Antikörper

Bindungsspezifität: AA 496-789

Spezifität: Reacts with human HIF 1 beta /ARNT

Kreuzreaktivität: Maus, Rind (Kuh), Schaf, Ratte (Rattus)

Kreuzreaktivität (Details): Cross reacts with proteins from bovine, sheep, mouse, rat and ferret. Not tested in other species.

Aufreinigung: Purified (protein G)

Immunogen: Fusion protein containing amino acids 496-789 of human HIF-1 beta

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
ChIP1:10-1:500, IHC1:100, IHC-P 1:100, WB 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.4 mg/mL

Buffer: PBS, Sodium azide 0.05 %

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Details zu ARNT

Target: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Andere Bezeichnung: Hypoxia-Inducible Factor 1-beta

Hintergrund: HIF-1 is a heterodimer composed of HIF-1 alpha and HIF-1 beta subunits which are bHLH proteins of PAS (PER, ARNT, SIM) family. HIF-1 beta forms heterodimer with AHR, AHRR, HIF1 alpha and EPAS1/HIF2 alpha as well as with other bHLH proteins and its dimerization is required for efficient DNA binding. Interact with TACC3 and NOCA7.

Gen-ID: 405

UniProt: P27540

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effekt