Der Kaninchen Polyklonal anti-EIF4B Antikörper (ABIN363082) detektiert spezifisch EIF4B in IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.
The antibody detects endogenous level of total eIF4B protein.
Aufreinigung
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
Immunogen
Peptide sequence around AA 420-424 (T-G-S-E-S) derived from Human eIF4B. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.