GRIA2 Antikörper (AA 878-882)

Produktnummer ABIN362994

Produktdetails anti-GRIA2 Antikörper

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Bindungsspezifität: AA 878-882

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: The antibody detects endogenous level of total Glutamate receptor 2 (Precursor) protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Peptide sequence around AA 878-882 (I-E-S-V-K) derived from Human Glutamate receptor 2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blotting: 1:500-1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu GRIA2

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Andere Bezeichnung: Glutamate receptor 2 (Precursor) (GRIA2 Produkte)

Synonyme: GLUR2 antikoerper, GLURB antikoerper, GluA2 antikoerper, GluR-K2 antikoerper, HBGR2 antikoerper, GluR-2 antikoerper, GluR-B antikoerper, Glur-2 antikoerper, Glur2 antikoerper, GluR2 antikoerper, gluR-B antikoerper, glur2a antikoerper, gria2.1 antikoerper, zfGRIA2[a] antikoerper, glur2 antikoerper, glutamate ionotropic receptor AMPA type subunit 2 antikoerper, glutamate receptor, ionotropic, AMPA 2 antikoerper, glutamate receptor, ionotropic, AMPA2 (alpha 2) antikoerper, glutamate receptor, ionotropic, AMPA 2a antikoerper, glutamate receptor, ionotropic, AMPA 2 S homeolog antikoerper, GRIA2 antikoerper, Gria2 antikoerper, gria2a antikoerper, gria2.S antikoerper

Hintergrund: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.

Molekulargewicht: 100 kDa

NCBI Accession: NP_000817

UniProt: P42262

Pathways: PI3K-Akt Signalweg