Der Kaninchen Polyklonal anti-BIM Antikörper (ABIN362986) detektiert spezifisch BIM in WB und IHC.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
The antibody detects endogenous level of total BIM protein.
Aufreinigung
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
Peptide sequence around AA 67-71 (P-A-S-P-G) derived from Human BIM. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-a1, isoform Bim-a2 and isoform Bim-a3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS.