FOXO4 Antikörper (AA 195-199)
Kurzübersicht für FOXO4 Antikörper (AA 195-199) (ABIN362777)
Target
Alle FOXO4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 195-199
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Spezifität
- The antibody detects endogenous level of total AFX protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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Immunogen
- Peptide sequence around AA 195-199 (A-A-S-M-D) derived from Human AFX. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotyp
- IgG
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Applikationshinweise
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- FOXO4 (Forkhead Box O4 (FOXO4))
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Andere Bezeichnung
- AFX
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Hintergrund
- Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.
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Molekulargewicht
- 65 kDa
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NCBI Accession
- NP_001164
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UniProt
- P98177
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Pathways
- Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation
Target
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