EIF4B Antikörper (pSer422)

Produktnummer ABIN362448

Produktdetails anti-EIF4B Antikörper

Target: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Bindungsspezifität: pSer422

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: The antibody detects endogenous level of eIF4B only when phosphorylated at Serine 422.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen: Peptide sequence around phosphorylation site of pSer422 (T-G-S (p) -E-S) derived from Human eIF4B. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu EIF4B

Target: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Andere Bezeichnung: eIF4B (EIF4B Produkte)

Synonyme: EIF-4B antikoerper, PRO1843 antikoerper, CG10837 antikoerper, Dm-eIF4B antikoerper, Dmel\\CG10837 antikoerper, Eif4B antikoerper, eIF-4B-L antikoerper, eIF-4B-S antikoerper, eIF-4b antikoerper, eIF4B antikoerper, eIF4B-L antikoerper, eIF4B-S antikoerper, eIf4b antikoerper, 2310046H11Rik antikoerper, AL024095 antikoerper, C85189 antikoerper, Eif4a2 antikoerper, eif4b antikoerper, fb15c09 antikoerper, wu:fb15c09 antikoerper, zgc:101532 antikoerper, MGC89384 antikoerper, eukaryotic translation initiation factor 4B antikoerper, eukaryotic initiation factor 4B antikoerper, Eukaryotic initiation factor 4B antikoerper, eukaryotic translation initiation factor 4Bb antikoerper, eukaryotic translation initiation factor 4Ba antikoerper, eukaryotic translation initiation factor 4B S homeolog antikoerper, EIF4B antikoerper, Eif4B antikoerper, eIF-4B antikoerper, Eif4b antikoerper, eif4bb antikoerper, eif4b antikoerper, eif4ba antikoerper, eif4b.S antikoerper, LOC100284982 antikoerper, LOC100380867 antikoerper

Hintergrund: Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Molekulargewicht: 80 kDa

NCBI Accession: NP_001408

UniProt: P23588