Der Kaninchen Polyklonal anti-Synaptotagmin Antikörper (ABIN362242) detektiert spezifisch Synaptotagmin in IF.
Dieser Antikörper reagiert spezifisch mit Proben aus Ratte, Maus und Human.
The antibody detects endogenous level of Synaptotagmin only when phosphorylated at serine 309.
Aufreinigung
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Immunogen
Peptide sequence around phosphorylation site of pSer309 (G-L-S (p) -D-P) derived from Human. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
SYT
Reaktivität: Ratte, Maus
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 350
Applikationshinweise
Immunofluorescence: 1:100-1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
Synaptotagmin (SYT)
Andere Bezeichnung
Synaptotagmin
Hintergrund
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse