JunB Antikörper (pSer79)

Produktnummer ABIN361924

Zitiert in 1 Publikation. Dieser Anti-JunB-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von JunB in IHC und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für JunB Antikörper (pSer79) (ABIN361924)

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JunB Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-JunB Antikörper

Bindungsspezifität: pSer79

Spezifität: The antibody detects endogenous level of JunB only when phosphorylated at serine 79.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed bychromatography using non-phosphopeptide corresponding to the phosphorylation site.

Immunogen: Peptide sequence around phosphorylation site of pSer79 (G-A-S (p) -L-K) derived from Human JunB. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Referenzen für anti-JunB Antikörper (ABIN361924)

Vartanian, Masri, Martin, Cloninger, Holmes, Artinian, Funk, Ruegg, Gera: "AP-1 regulates cyclin D1 and c-MYC transcription in an AKT-dependent manner in response to mTOR inhibition: role of AIP4/Itch-mediated JUNB degradation." in: Molecular cancer research : MCR, Vol. 9, Issue 1, pp. 115-30, (2011) (PubMed).

Details zu JunB

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Andere Bezeichnung: JunB

Hintergrund: Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGA[CG]TCA-3'.

Molekulargewicht: 43 kDa

NCBI Accession: NP_002220

UniProt: P17275