SYN1 Antikörper (pSer62, pSer67)

Produktnummer ABIN361494

Dieser Anti-SYN1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von SYN1 in WB und ELISA. Geeignet für Ratte. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für SYN1 Antikörper (pSer62, pSer67) (ABIN361494)

Target: SYN1 (Synapsin I (SYN1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SYN1 Antikörper

Bindungsspezifität: pSer62, pSer67

Spezifität: Specific for endogenous levels of the ~78 kDa synapsin I doublet phosphorylated at Ser62,67. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.

Kreuzreaktivität: Human, Maus, Ratte

Homologie: bovine, mouse

Produktmerkmale: Our Synapsin (Ser62,67) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Synapsin (Ser62,67) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Aufreinigung: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser62/67 of rat synapsin, conjugated to keyhole limpet hemocyanin (KLH).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Haltbarkeit: 12 months

Referenzen für anti-SYN1 Antikörper (ABIN361494)

Chanaday, Vilcaes, de Paul, Torres, Degano, Roth: "Glutamate release machinery is altered in the frontal cortex of rats with experimental autoimmune encephalomyelitis." in: Molecular neurobiology, Vol. 51, Issue 3, pp. 1353-67, (2015) (PubMed).

Leal-Ortiz, Waites, Terry-Lorenzo, Zamorano, Gundelfinger, Garner: "Piccolo modulation of Synapsin1a dynamics regulates synaptic vesicle exocytosis." in: The Journal of cell biology, Vol. 181, Issue 5, pp. 831-46, (2008) (PubMed).

Tallent, Varghis, Skorobogatko, Hernandez-Cuebas, Whelan, Vocadlo, Vosseller: "In vivo modulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation." in: The Journal of biological chemistry, Vol. 284, Issue 1, pp. 174-81, (2008) (PubMed).

Details zu SYN1

Target: SYN1 (Synapsin I (SYN1))

Andere Bezeichnung: SYN1

Hintergrund:

Synonyms: Brain protein 4.1 antibody, SYN 1 antibody, SYN 1a antibody, SYN 1b antibody, SYN I antibody, SYN1 antibody, SYN1_HUMAN antibody, SYN1a antibody, SYN1b antibody, Synapsin 1 antibody, Synapsin I antibody, Synapsin-1 antibody, Synapsin1 antibody, SynapsinI antibody, SYNI antibody

Description Logic: Our Synapsin (Ser62,67) rabbit polyclonal phosphospecific primary antibody is produced . It detects Synapsin (Ser62,67) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: SYN1

Molekulargewicht: 78 kDa

Gen-ID: 281510

UniProt: P17599