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RPH3A Antikörper (pSer234)

RPH3A Reaktivität: Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN361489
  • Target Alle RPH3A Antikörper anzeigen
    RPH3A (Rabphilin 3A (RPH3A))
    Bindungsspezifität
    • 12
    • 10
    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer234
    Reaktivität
    • 40
    • 28
    • 25
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 47
    Kaninchen
    Klonalität
    • 47
    Polyklonal
    Konjugat
    • 30
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RPH3A Antikörper ist unkonjugiert
    Applikation
    • 38
    • 19
    • 12
    • 9
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    Specific for the ~82k rabphilin protein phosphorylated at Ser234. The immunolabeling of the rabphilin band was completely blocked by the phosphopeptide used as antigen while the dephosphopeptide had no effect on the immunolabeling
    Kreuzreaktivität
    Ratte (Rattus)
    Homologie
    mouse
    Aufreinigung
    Antigen Affinity Purified from Pooled Serum
    Immunogen
    Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser234 conjugated to KLH
    Top Product
    Discover our top product RPH3A Primärantikörper
  • Applikationshinweise
    Recommended Dilution: WB: 1:1000 IHC: 1:400 Quality Control: Western blots performed on each lot.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
    Lagerung
    -20 °C
  • Stephens, Powell, Taraska, Harris: "Imaging the rapid yet transient accumulation of regulatory lipids, lipid kinases, and protein kinases during membrane fusion, at sites of exocytosis of MMP-9 in MCF-7 cells." in: Lipids in health and disease, Vol. 19, Issue 1, pp. 195, (2020) (PubMed).

  • Target
    RPH3A (Rabphilin 3A (RPH3A))
    Andere Bezeichnung
    RPH3A (RPH3A Produkte)
    Synonyme
    2900002P20Rik antikoerper, AU022689 antikoerper, AW108370 antikoerper, CG11556 antikoerper, Dmel\\CG11556 antikoerper, exophilin-1 antikoerper, fc61h10 antikoerper, rph3a antikoerper, wu:fc61h10 antikoerper, rabphilin 3A antikoerper, Rabphilin antikoerper, rabphilin-3a, putative antikoerper, rabphilin-3A antikoerper, rabphilin 3A S homeolog antikoerper, rabphilin 3A homolog (mouse), a antikoerper, RPH3A antikoerper, Rph3a antikoerper, Rph antikoerper, Smp_145120 antikoerper, Tsp_00335 antikoerper, rph3a.S antikoerper, rph3aa antikoerper
    Hintergrund
    Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994,Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington’s disease(Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995,Foletti and Scheller, 2001). Anti-Phospho-Ser234 Rabphilin 3A Western blot of rat brain lysate showing specific immunolabeling of the ~82k rabphilin 3A phosphorylated at Ser234.
    Molekulargewicht
    '82 kDa
    Gen-ID
    171039
    UniProt
    P47709
    Pathways
    Synaptic Vesicle Exocytosis
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