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Vimentin Antikörper

VIM Reaktivität: Human WB, IF Wirt: Huhn Polyclonal unconjugated
Produktnummer ABIN361371
  • Target Alle Vimentin (VIM) Antikörper anzeigen
    Vimentin (VIM)
    Reaktivität
    • 326
    • 126
    • 125
    • 60
    • 59
    • 44
    • 43
    • 37
    • 30
    • 22
    • 20
    • 14
    • 13
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 187
    • 124
    • 9
    • 6
    • 4
    • 4
    • 2
    Huhn
    Klonalität
    • 198
    • 137
    Polyklonal
    Konjugat
    • 193
    • 19
    • 13
    • 13
    • 10
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser Vimentin Antikörper ist unkonjugiert
    Applikation
    • 275
    • 127
    • 99
    • 95
    • 95
    • 59
    • 46
    • 40
    • 39
    • 28
    • 23
    • 18
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Spezifität
    Specific for the ~50kDa Vimentin protein. It is expected that it will work on other mammalian tissues.
    Kreuzreaktivität
    Rind (Kuh), Human, Maus, Ratte (Rattus)
    Aufreinigung
    Total IgY fraction
    Immunogen
    Recombinant human vimentin purified from E. coli
    Top Product
    Discover our top product VIM Primärantikörper
  • Applikationshinweise
    Recommended Dilution: WB: 1:1,000 IF: 1:500 Quality Control: Western blots performed on each lot.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    total IgY fraction in PBS + 10 mM Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Kirane, Toombs, Larsen, Ostapoff, Meshaw, Zaknoen, Brekken, Burrows: "Epithelial-mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib." in: Carcinogenesis, Vol. 33, Issue 9, pp. 1639-46, (2012) (PubMed).

    Kirane, Toombs, Ostapoff, Carbon, Zaknoen, Braunfeld, Schwarz, Burrows, Brekken: "Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 18, pp. 5031-42, (2012) (PubMed).

  • Target
    Vimentin (VIM)
    Andere Bezeichnung
    VIM (VIM Produkte)
    Synonyme
    CTRCT30 antikoerper, cb28 antikoerper, vime antikoerper, vim antikoerper, vim1 antikoerper, vim2 antikoerper, VIM antikoerper, Vimentin antikoerper, vim4 antikoerper, vimentin antikoerper, vimentin L homeolog antikoerper, vimentin S homeolog antikoerper, VIM antikoerper, Vim antikoerper, vim antikoerper, vim.L antikoerper, vim.S antikoerper
    Hintergrund
    Vimentin is the major protein subunit of the 10nm or intermediate filaments (IFs) found in many kinds of mesenchymal and epithelial cells as well as developing neuronal and astrocytic precursor cells in the CNS. Vimentin is thought to be critically involved in lymphocyte adhesion and transmigration (Nieminen M et al. 2006). Copolymers are frequently formed between vimentin and other IFs, such as GFAP (in many kinds of astrocytes), desmin (in muscle cells) and neurofilament proteins (in developing neurons). Antibodies to vimentin are useful in studies of stem cells and generally to reveal the filamentous cytoskeleton. Recent studies suggest that vimentin affects prostate cancer cells motility and invasiveness (Zhao et al. 2008).
    Molekulargewicht
    '50 kDa
    Gen-ID
    7431
    UniProt
    P08670
    Pathways
    Caspase Kaskade in der Apoptose
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