PLAUR Antikörper

Produktnummer ABIN360948

Der Ratte Monoklonal anti-PLAUR Antikörper (Klon 7J34) (ABIN360948) detektiert spezifisch PLAUR in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für PLAUR Antikörper (ABIN360948)

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser PLAUR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 7J34

Produktdetails anti-PLAUR Antikörper

Spezifität: This antibody detects uPAR.

Aufreinigung: Protein A/G Affinity Chromatography

Immunogen: Purified Mouse Recombinant uPAR

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: PBS, None

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PLAUR

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Andere Bezeichnung: CD87 / uPAR

Hintergrund: UPAR (Urokinase plasminogen activator receptor) is a glycoprotein I anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum beta globulin plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.Synonyms: MO3, Monocyte activation antigen Mo3, PLAUR, U-PAR, Urokinase plasminogen activator surface receptor

Gen-ID: 18793

NCBI Accession: NP_035243

UniProt: P35456

Pathways: Inositol Metabolic Process