Thymic Stromal Lymphopoietin Antikörper

Produktnummer ABIN360946

Dieser Ratte Monoklonal Antikörper detektiert spezifisch Thymic Stromal Lymphopoietin in WB. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für Thymic Stromal Lymphopoietin Antikörper (ABIN360946)

Target: Thymic Stromal Lymphopoietin (TSLP)

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Thymic Stromal Lymphopoietin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 5G29

Produktdetails anti-Thymic Stromal Lymphopoietin Antikörper

Spezifität: This antibody detects Mouse TSLP. Other species not tested.

Aufreinigung: Protein A/G Affinity Chromatography

Immunogen: Purified Mouse Recombinant TSLP

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: PBS, None

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Thymic Stromal Lymphopoietin

Target: Thymic Stromal Lymphopoietin (TSLP)

Andere Bezeichnung: TSLP

Hintergrund: Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. The activities of mouse TSLP overlap with, but are distinct from, those of mouse IL-7. Both mouse TSLP and IL-7 can co-stimulate growth of thymocytes and mature T cells, and support B lymphopoiesis in long-term cultures of fetal liver cells and bone-marrow cells. Whereas mouse IL-7 facilitates the development of B220+/IgM- pre-B cells, mouse TSLP promotes the development B220+/IgM+ B cells. Human TSLP was reported to preferentially stimulate myeloid cells, inducing the release of T cell-attracting chemokines from monocytes and enhancing the maturation of CD11c+ dendritic cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence. Within the mature region, six of the seven cysteine residues present in the mouse TSLP involved in intramolecular disulfide bond formation are conserved in the human TSLP. Human TSLP shares approximately 43 % aa sequence identity with mouse TSLP.Synonyms: Thymic stroma-derived lymphopoietin, Thymic stromal lymphopoietin

Gen-ID: 53603

NCBI Accession: NP_067342

UniProt: Q9JIE6