Leptin Receptor Antikörper (Extracellular Domain)

Produktnummer ABIN360927

Dieses Anti-Leptin Receptor-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von Leptin Receptor in WB. Geeignet für Maus.

Kurzübersicht für Leptin Receptor Antikörper (Extracellular Domain) (ABIN360927)

Target: Leptin Receptor (LEPR)

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Leptin Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 9C29

Produktdetails anti-Leptin Receptor Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: This antibody detects Leptin receptor.

Aufreinigung: Protein A/G affinity chromatography

Immunogen: Recombinant Leptin R extracellular domain.

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Leptin Receptor

Target: Leptin Receptor (LEPR)

Andere Bezeichnung: CD295 / Leptin Receptor

Hintergrund: Leptin receptor (OB-R) is a type I cytokine receptor family protein with significant amino acid sequence identity with gp130, G-CSF receptor, and LIF receptor. An OB-R transcript encodes a soluble form of the receptor. The transcript was reported to be expressed predominantly in regions of the hypothalamus previously thought to be important in body weight regulation. OB-R binds leptin with high affinity and is a potent leptin antagonist. Human OB-R encodes a 1 165 amino acid residue precursor protein with a 22 amino acid residue signal peptide, an 816 amino acid residue extracellular domain, a 21 amino acid residue transmembrane domain and a 303 amino acid residue cytoplasmic domain.Synonyms: DB, HuB219, LEP-R, LEPR, OB receptor, OB-R, OBR

Gen-ID: 16847

NCBI Accession: NP_001116371

UniProt: P48356

Pathways: JAK-STAT Signalweg, AMPK Signaling, Feeding Behaviour