JAM2 Antikörper (Extracellular Domain)

Produktnummer ABIN360922

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch JAM2 in WB. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für JAM2 Antikörper (Extracellular Domain) (ABIN360922)

Target: JAM2 (Junctional Adhesion Molecule 2 (JAM2))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser JAM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 2K15

Produktdetails anti-JAM2 Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: This antibody detects Mouse JAM-B in Western blotting. Other species not tested.

Aufreinigung: Purified

Immunogen: Recombinant protein of JAM-A extracellular domain

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 0.2 mL sterile PBS and the final concentration is 0.5 mg/mL.

Buffer: 0.2 μm filtered PBS, None

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu JAM2

Target: JAM2 (Junctional Adhesion Molecule 2 (JAM2))

Andere Bezeichnung: CD322 / JAM2

Hintergrund: Members of the junctional adhesion molecule (JAM) family are type I transmembrane glycoproteins of the immunoglobulin (Ig) superfamily that are localized in the tight junctions between endothelial or epithelial cells and appear to be involved in leukocyte transmigration. JAM-A, also known as platelet adhesion molecule 1 (PAM-1) and platelet F11 receptor, contains two V-type Ig-like domains, forms homodimers, and interacts with LFA-1. JAM-B (vasculoendothelial or VE-JAM) and JAM-C each contain two Ig domains (one V-type and one C2-type), a cytoplasmic PDZ-binding motif and a PKC phosphorylation site. JAM-C interacts with MAC-1 and facilitates JAM-B interaction with integrin alpha 4 beta 1. Junctional adhesion molecule 2 (JAM2), also know as JAMB, is a member of the newly reported glycoprotein family of adhesion molecules found at intercellular junctions of endothelial cells and lymphocytes (human). In adult murine tissue JAM2 expression is restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney.Synonyms: C21orf43, JAM-B, Junctional adhesion molecule 2, Junctional adhesion molecule B, VEJAM, Vascular endothelial junction-associated molecule

Gen-ID: 67374

NCBI Accession: NP_076333

UniProt: Q9JI59