F11R Antikörper (Extracellular Domain)

Produktnummer ABIN360921

Dieses Anti-F11R-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von F11R in WB. Geeignet für Maus.

Kurzübersicht für F11R Antikörper (Extracellular Domain) (ABIN360921)

Target: F11R (F11 Receptor (F11R))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser F11R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1M21

Produktdetails anti-F11R Antikörper

Bindungsspezifität: Extracellular Domain

Aufreinigung: Purified

Immunogen: Recombinant protein of JAM-A extracellular domain

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: Protein A/G affinity chromatography

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu F11R

Target: F11R (F11 Receptor (F11R))

Andere Bezeichnung: CD321 / JAM1

Hintergrund: Junctional Adhesion Molecule 1 (JAM1) seems to play a role in epithelial tight junction formation. It appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. JAM1 plays a role in regulating monocyte transmigration involved in integrity of the epithelial barrier. JAM1 is also involved in platelet activation.Synonyms: F11R, JAM-A, JCAM, Junctional adhesion molecule 1, Junctional adhesion molecule A, PAM1, Platelet F11 receptor, Platelet adhesion molecule 1

Gen-ID: 10090

UniProt: O88792

Pathways: Cell-Cell Junction Organization