IL2 Receptor beta Antikörper (Extracellular Domain)

Produktnummer ABIN360905

Der Ratte Monoklonal Anti-IL2 Receptor beta-Antikörper wurde für WB validiert. Er ist geeignet, IL2 Receptor beta in Proben von Maus zu detektieren.

Kurzübersicht für IL2 Receptor beta Antikörper (Extracellular Domain) (ABIN360905)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL2 Receptor beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 9-00E-033

Produktdetails anti-IL2 Receptor beta Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: This antibody detects IL-2Rbeta.

Aufreinigung: Protein A/G affinity chromatography

Immunogen: Recombinant protein of IL-2Rbeta extracellular domain.

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Andere Bezeichnung: CD122 / IL2RB

Hintergrund: IL2 Receptor beta (CD122) is a member of the immunoglobulin superfamily that forms the high affinity IL2 receptor with CD25 and CD132. This receptor chain, which is also shared by the IL15 receptor, is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL2 Receptor beta chain can combine with either the common gamma subunit (gamma c) alone or the gamma c subunit and the IL2 Receptor alpha subunit to generate intermediate or high affinity IL2 receptor complexes, respectively. CD122 levels can be upregulated by activation stimuli such as IL2.Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75

Gen-ID: 16185

NCBI Accession: NP_032394

UniProt: P16297

Pathways: JAK-STAT Signalweg, Growth Factor Binding