EDAR Antikörper (Extracellular Domain)
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- Target Alle EDAR Antikörper anzeigen
- EDAR (Ectodysplasin A Receptor (EDAR))
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Bindungsspezifität
- Extracellular Domain
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Reaktivität
- Human, Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser EDAR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- This antibody detects EDAR and cross reacts with human EDAR.
- Aufreinigung
- Protein A/G affinity chromatography
- Immunogen
- Recombinant extracellular domain of EDAR
- Klon
- 9A38
- Isotyp
- IgG2
- Top Product
- Discover our top product EDAR Primärantikörper
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- Applikationshinweise
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- EDAR (Ectodysplasin A Receptor (EDAR))
- Andere Bezeichnung
- EDAR (EDAR Produkte)
- Synonyme
- rs3 antikoerper, edar antikoerper, EDAR antikoerper, MGC88893 antikoerper, DL antikoerper, ECTD10A antikoerper, ECTD10B antikoerper, ED1R antikoerper, ED3 antikoerper, ED5 antikoerper, EDA-A1R antikoerper, EDA1R antikoerper, EDA3 antikoerper, HRM1 antikoerper, dl antikoerper, RGD1561714 antikoerper, ectodysplasin A receptor antikoerper, ectodysplasin-A receptor antikoerper, edar antikoerper, EDAR antikoerper, Edar antikoerper
- Hintergrund
- EDAR (Ectodysplasin A receptor) is a receptor for EDA isoform A1, but not for EDA isoform A2. It has a single transmembrane domain, and shows similarity to 2 separate domains of the tumor necrosis factor (TNF) receptor (TNFR) family. It mediates the activation of NF-kappa-B and JNK and may promote caspase independent cell death. Defects in EDAR are a cause of hypohidrotic ectodermal dysplasia.Synonyms: Anhidrotic ectodysplasin receptor 1, DL, Downless homolog, ED1R, ED3, ED5, EDA-A1 receptor, EDA-A1R, EDA1R, EDA3, Ectodermal dysplasia receptor, Ectodysplasin-A receptor, FLJ94390, HRM1, Tumor necrosis factor receptor superfamily member EDAR
- Gen-ID
- 13608
- NCBI Accession
- NP_034230
- UniProt
- Q9R187
- Pathways
- Tube Formation, Ubiquitin Proteasome Pathway
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