EDAR Antikörper (Extracellular Domain)

Produktnummer ABIN360882

Dieses Anti-EDAR-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von EDAR in WB. Geeignet für Human und Maus.

Kurzübersicht für EDAR Antikörper (Extracellular Domain) (ABIN360882)

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Reaktivität: Human, Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser EDAR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 9A38

Produktdetails anti-EDAR Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: This antibody detects EDAR and cross reacts with human EDAR.

Aufreinigung: Protein A/G affinity chromatography

Immunogen: Recombinant extracellular domain of EDAR

Isotyp: IgG2

Anwendungsinformationen

Applikationshinweise: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu EDAR

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Andere Bezeichnung: EDAR

Hintergrund: EDAR (Ectodysplasin A receptor) is a receptor for EDA isoform A1, but not for EDA isoform A2. It has a single transmembrane domain, and shows similarity to 2 separate domains of the tumor necrosis factor (TNF) receptor (TNFR) family. It mediates the activation of NF-kappa-B and JNK and may promote caspase independent cell death. Defects in EDAR are a cause of hypohidrotic ectodermal dysplasia.Synonyms: Anhidrotic ectodysplasin receptor 1, DL, Downless homolog, ED1R, ED3, ED5, EDA-A1 receptor, EDA-A1R, EDA1R, EDA3, Ectodermal dysplasia receptor, Ectodysplasin-A receptor, FLJ94390, HRM1, Tumor necrosis factor receptor superfamily member EDAR

Gen-ID: 13608

NCBI Accession: NP_034230

UniProt: Q9R187

Pathways: Tube Formation, Ubiquitin Proteasome Pathway