PPM1F Antikörper (C-Term)

Produktnummer ABIN360801

Produktdetails anti-PPM1F Antikörper

Target: PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPM1F Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to PPM1F.

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PPM1F.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu PPM1F

Target: PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))

Andere Bezeichnung: Protein Phosphatase 1F / PPM1F (PPM1F Produkte)

Synonyme: 1110021B16Rik antikoerper, 4933427B07Rik antikoerper, CaMKPase antikoerper, Popx2 antikoerper, mKIAA0015 antikoerper, CAMKP antikoerper, FEM-2 antikoerper, POPX2 antikoerper, hFEM-2 antikoerper, protein phosphatase, Mg2+/Mn2+ dependent 1F antikoerper, protein phosphatase 1F (PP2C domain containing) antikoerper, protein phosphatase, Mg2+/Mn2+ dependent, 1F antikoerper, PPM1F antikoerper, Ppm1f antikoerper

Hintergrund: PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.Synonyms: Ca(2+)/calmodulin-dependent protein kinase phosphatase, CaM-kinase phosphatase, CaMKPase, KIAA0015, POPX2, Partner of PIX 2, Protein fem-2 homolog

Gen-ID: 9647, 9606

UniProt: P49593

Pathways: Positive Regulation of Endopeptidase Activity